Journal: International Journal of Molecular Sciences

Article Title: Multiomic Profiling Identified EGF Receptor Signaling as a Potential Inhibitor of Type I Interferon Response in Models of Oncolytic Therapy by Vesicular Stomatitis Virus

doi: 10.3390/ijms23095244

Figure Lengend Snippet: Type I interferon signaling pathway is enriched by differentially expressed genes in available RNA seq datasets obtained for cancer cell lines treated with gefitinib [ 36 , 38 ]. Pathways were generated by Reactome [ 39 ] and Gene Ontology [ 40 ]. The “Enrichment rank” means a rank in a list sorted by enrichment’s p -value.

Article Snippet: As primary antibodies, anti-beta-actin sc-47778 diluted at 1:3500 (Santa Cruz Biotechnology, Santa Cruz, CA, USA) and ErbB2/Her2 Antibody AF1129 diluted at 1:3000 (R&D Systems, Minneapolis, MN, USA) were used for actin control and HER2 detection, respectively.

Techniques: RNA Sequencing, Generated